null

SMILES: CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@H]1C)C(F)(F)F

InChI Key: InChIKey=PJYAGXNGZCEMKT-PRHODGIISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50076703 ((7R,8R)-8-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@H]1C)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t8-,12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076703 ((7R,8R)-8-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@H]1C)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t8-,12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076703 ((7R,8R)-8-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C[C@H]1C)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(22)21-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3,(H,21,22)/t8-,12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair