null

SMILES: CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F

InChI Key: InChIKey=FXDBHLKOPNALNO-CQSZACIVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50076715 ((R)-8-Ethyl-7,7-dimethyl-4-trifluoromethyl-6,7,8,9...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-4-14-16(2,3)8-9-5-10-11(17(18,19)20)6-15(23)22-13(10)7-12(9)21-14/h5-7,14,21H,4,8H2,1-3H3,(H,22,23)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076715 ((R)-8-Ethyl-7,7-dimethyl-4-trifluoromethyl-6,7,8,9...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-4-14-16(2,3)8-9-5-10-11(17(18,19)20)6-15(23)22-13(10)7-12(9)21-14/h5-7,14,21H,4,8H2,1-3H3,(H,22,23)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076715 ((R)-8-Ethyl-7,7-dimethyl-4-trifluoromethyl-6,7,8,9...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(C)C)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-4-14-16(2,3)8-9-5-10-11(17(18,19)20)6-15(23)22-13(10)7-12(9)21-14/h5-7,14,21H,4,8H2,1-3H3,(H,22,23)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair