BDBM50077165 2-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}phenyl-iminomethanamine::CHEMBL51824

SMILES: NC(=N)c1ccc(Oc2cccc(Oc3ccccc3C(N)=N)n2)cc1

InChI Key: InChIKey=OWCKBLKNIPDMGZ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50077165 (2-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...) Show SMILES NC(=N)c1ccc(Oc2cccc(Oc3ccccc3C(N)=N)n2)cc1 Show InChI InChI=1S/C19H17N5O2/c20-18(21)12-8-10-13(11-9-12)25-16-6-3-7-17(24-16)26-15-5-2-1-4-14(15)19(22)23/h1-11H,(H3,20,21)(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Compound was tested for inhibition activity against Coagulation factor X				J Med Chem 42: 1749-56 (1999) Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50077165 (2-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...) Show SMILES NC(=N)c1ccc(Oc2cccc(Oc3ccccc3C(N)=N)n2)cc1 Show InChI InChI=1S/C19H17N5O2/c20-18(21)12-8-10-13(11-9-12)25-16-6-3-7-17(24-16)26-15-5-2-1-4-14(15)19(22)23/h1-11H,(H3,20,21)(H3,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Compound was tested for inhibition activity against human thrombin (FIIa)				J Med Chem 42: 1749-56 (1999) Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF
					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50077165 (2-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...) Show SMILES NC(=N)c1ccc(Oc2cccc(Oc3ccccc3C(N)=N)n2)cc1 Show InChI InChI=1S/C19H17N5O2/c20-18(21)12-8-10-13(11-9-12)25-16-6-3-7-17(24-16)26-15-5-2-1-4-14(15)19(22)23/h1-11H,(H3,20,21)(H3,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Compound was tested for inhibition activity against bovine trypsin.				J Med Chem 42: 1749-56 (1999) Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF
					More data for this Ligand-Target Pair