BDBM50077904 CHEMBL3417065
SMILES: Fc1ccc(Cn2cc(NCCN3CCOCC3)nn2)cc1F
InChI Key: InChIKey=IHXGZVXMQKYCLA-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50077904![]() (CHEMBL3417065) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 878 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Esteve Curated by ChEMBL | Assay Description Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation counting | J Med Chem 58: 2441-51 (2015) Article DOI: 10.1021/jm501920g BindingDB Entry DOI: 10.7270/Q29C704N | |||||||||||
More data for this Ligand-Target Pair |