BDBM50077976 4-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)-phenol::4-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-4-yl)phenol::CHEMBL68215

SMILES: Oc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1

InChI Key: InChIKey=PAXXIJHKIXSMOM-UHFFFAOYSA-N

Data: 2 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50077976 (4-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)-pheno...) Show SMILES Oc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1 Show InChI InChI=1S/C20H15N3O/c24-17-8-6-14(7-9-17)18-19(15-10-12-21-13-11-15)23-20(22-18)16-4-2-1-3-5-16/h1-13,24H,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human RAF proto-oncogene serine/threonine-protein kinase				J Med Chem 42: 2180-90 (1999) Article DOI: 10.1021/jm9805236 BindingDB Entry DOI: 10.7270/Q2Q81C8D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50077976 (4-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)-pheno...) Show SMILES Oc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1 Show InChI InChI=1S/C20H15N3O/c24-17-8-6-14(7-9-17)18-19(15-10-12-21-13-11-15)23-20(22-18)16-4-2-1-3-5-16/h1-13,24H,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition bRaf kinase activity				Bioorg Med Chem Lett 16: 378-81 (2005) Article DOI: 10.1016/j.bmcl.2005.09.072 BindingDB Entry DOI: 10.7270/Q2Z038Z9
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50077976 (4-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)-pheno...) Show SMILES Oc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1 Show InChI InChI=1S/C20H15N3O/c24-17-8-6-14(7-9-17)18-19(15-10-12-21-13-11-15)23-20(22-18)16-4-2-1-3-5-16/h1-13,24H,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity at bRaf kinase in fluorescent ligand displacement assay				Bioorg Med Chem Lett 16: 378-81 (2005) Article DOI: 10.1016/j.bmcl.2005.09.072 BindingDB Entry DOI: 10.7270/Q2Z038Z9
					More data for this Ligand-Target Pair