BDBM50078776 CHEMBL3416150

SMILES: Fc1ccc(cc1C#N)-c1cnc2cc(ccn12)-c1ccco1

InChI Key: InChIKey=DOUUYDDRCWCEMJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50078776 (CHEMBL3416150) Show SMILES Fc1ccc(cc1C#N)-c1cnc2cc(ccn12)-c1ccco1 Show InChI InChI=1S/C18H10FN3O/c19-15-4-3-12(8-14(15)10-20)16-11-21-18-9-13(5-6-22(16)18)17-2-1-7-23-17/h1-9,11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...				Eur J Med Chem 94: 123-31 (2015) Article DOI: 10.1016/j.ejmech.2015.02.052 BindingDB Entry DOI: 10.7270/Q2Z039VC
					More data for this Ligand-Target Pair