BDBM50078784 4-[(4-octyl-1,3-thiazol-2-yl)amino]-N-phenylbenzene-1-sulfonamide::CHEMBL53679

SMILES: CCCCCCCCc1csc(Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)n1

InChI Key: InChIKey=KETXQKATKDHLAH-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50078784 (4-[(4-octyl-1,3-thiazol-2-yl)amino]-N-phenylbenzen...) Show SMILES CCCCCCCCc1csc(Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)n1 Show InChI InChI=1S/C23H29N3O2S2/c1-2-3-4-5-6-8-13-21-18-29-23(25-21)24-19-14-16-22(17-15-19)30(27,28)26-20-11-9-7-10-12-20/h7,9-12,14-18,26H,2-6,8,13H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cAMP...				Bioorg Med Chem Lett 9: 1869-74 (1999) BindingDB Entry DOI: 10.7270/Q2FN15D1
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50078784 (4-[(4-octyl-1,3-thiazol-2-yl)amino]-N-phenylbenzen...) Show SMILES CCCCCCCCc1csc(Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)n1 Show InChI InChI=1S/C23H29N3O2S2/c1-2-3-4-5-6-8-13-21-18-29-23(25-21)24-19-14-16-22(17-15-19)30(27,28)26-20-11-9-7-10-12-20/h7,9-12,14-18,26H,2-6,8,13H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cAMP...				Bioorg Med Chem Lett 9: 1869-74 (1999) BindingDB Entry DOI: 10.7270/Q2FN15D1
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50078784 (4-[(4-octyl-1,3-thiazol-2-yl)amino]-N-phenylbenzen...) Show SMILES CCCCCCCCc1csc(Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)n1 Show InChI InChI=1S/C23H29N3O2S2/c1-2-3-4-5-6-8-13-21-18-29-23(25-21)24-19-14-16-22(17-15-19)30(27,28)26-20-11-9-7-10-12-20/h7,9-12,14-18,26H,2-6,8,13H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro agonistic activity against cloned human beta-3 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cA...				Bioorg Med Chem Lett 9: 1869-74 (1999) BindingDB Entry DOI: 10.7270/Q2FN15D1
					More data for this Ligand-Target Pair