BDBM50078839 CHEMBL3416156

SMILES: Cc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccccc1

InChI Key: InChIKey=HXVMUJKLKWASFV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50078839 (CHEMBL3416156) Show SMILES Cc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccccc1 Show InChI InChI=1S/C20H16N2/c1-15-7-9-17(10-8-15)19-14-21-20-13-18(11-12-22(19)20)16-5-3-2-4-6-16/h2-14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...				Eur J Med Chem 94: 123-31 (2015) Article DOI: 10.1016/j.ejmech.2015.02.052 BindingDB Entry DOI: 10.7270/Q2Z039VC
					More data for this Ligand-Target Pair