BDBM50079037 6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-pyridine-2-carboxylic acid::CHEMBL85079

SMILES: NS(=O)(=O)c1nnc(NC(=O)c2cccc(n2)C(O)=O)s1

InChI Key: InChIKey=AQULIWLSIITFDZ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50079037 (6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-py...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)c2cccc(n2)C(O)=O)s1 Show InChI InChI=1S/C9H7N5O5S2/c10-21(18,19)9-14-13-8(20-9)12-6(15)4-2-1-3-5(11-4)7(16)17/h1-3H,(H,16,17)(H2,10,18,19)(H,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant carbonic anhydrase II				J Med Chem 42: 2641-50 (1999) Article DOI: 10.1021/jm9900523 BindingDB Entry DOI: 10.7270/Q2J67HMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Bos taurus (bovine))	BDBM50079037 (6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-py...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)c2cccc(n2)C(O)=O)s1 Show InChI InChI=1S/C9H7N5O5S2/c10-21(18,19)9-14-13-8(20-9)12-6(15)4-2-1-3-5(11-4)7(16)17/h1-3H,(H,16,17)(H2,10,18,19)(H,12,13,15)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).				J Med Chem 42: 2641-50 (1999) Article DOI: 10.1021/jm9900523 BindingDB Entry DOI: 10.7270/Q2J67HMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50079037 (6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-py...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)c2cccc(n2)C(O)=O)s1 Show InChI InChI=1S/C9H7N5O5S2/c10-21(18,19)9-14-13-8(20-9)12-6(15)4-2-1-3-5(11-4)7(16)17/h1-3H,(H,16,17)(H2,10,18,19)(H,12,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human cloned carbonic anhydrase isozyme I (hCA I, cytosolic form).				J Med Chem 42: 2641-50 (1999) Article DOI: 10.1021/jm9900523 BindingDB Entry DOI: 10.7270/Q2J67HMK
					More data for this Ligand-Target Pair