BDBM50079177 5-Methyl-1-(1-phenethyl-piperidin-4-yl)-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL91229

SMILES: Cc1c([nH]c(=O)n1C1CCN(CCc2ccccc2)CC1)-c1ccccc1

InChI Key: InChIKey=GIYXEZZPINFSPU-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079177 (5-Methyl-1-(1-phenethyl-piperidin-4-yl)-4-phenyl-1...) Show SMILES Cc1c([nH]c(=O)n1C1CCN(CCc2ccccc2)CC1)-c1ccccc1 Show InChI InChI=1S/C23H27N3O/c1-18-22(20-10-6-3-7-11-20)24-23(27)26(18)21-13-16-25(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,21H,12-17H2,1H3,(H,24,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D4 stably expressed in HEK-393 cell lines				J Med Chem 42: 2706-15 (1999) Article DOI: 10.1021/jm991029k BindingDB Entry DOI: 10.7270/Q2P55MPV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50079177 (5-Methyl-1-(1-phenethyl-piperidin-4-yl)-4-phenyl-1...) Show SMILES Cc1c([nH]c(=O)n1C1CCN(CCc2ccccc2)CC1)-c1ccccc1 Show InChI InChI=1S/C23H27N3O/c1-18-22(20-10-6-3-7-11-20)24-23(27)26(18)21-13-16-25(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,21H,12-17H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D2 stably expressed in CHO cell lines				J Med Chem 42: 2706-15 (1999) Article DOI: 10.1021/jm991029k BindingDB Entry DOI: 10.7270/Q2P55MPV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50079177 (5-Methyl-1-(1-phenethyl-piperidin-4-yl)-4-phenyl-1...) Show SMILES Cc1c([nH]c(=O)n1C1CCN(CCc2ccccc2)CC1)-c1ccccc1 Show InChI InChI=1S/C23H27N3O/c1-18-22(20-10-6-3-7-11-20)24-23(27)26(18)21-13-16-25(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,21H,12-17H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D3 (hD3) stably expressed in HEK-393 cell lines				J Med Chem 42: 2706-15 (1999) Article DOI: 10.1021/jm991029k BindingDB Entry DOI: 10.7270/Q2P55MPV
					More data for this Ligand-Target Pair