BDBM50079298 3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid [3-(4-methyl-piperazin-1-yl)-propyl]-amide::CHEMBL318068

SMILES: CC(C)n1c2ccccc2n(C(=O)NCCCN2CCN(C)CC2)c1=O

InChI Key: InChIKey=KQHKXGVTZYASSA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50079298 (3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...) Show SMILES CC(C)n1c2ccccc2n(C(=O)NCCCN2CCN(C)CC2)c1=O Show InChI InChI=1S/C19H29N5O2/c1-15(2)23-16-7-4-5-8-17(16)24(19(23)26)18(25)20-9-6-10-22-13-11-21(3)12-14-22/h4-5,7-8,15H,6,9-14H2,1-3H3,(H,20,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FAES, S.A. Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 3 receptor in rat enthorinal cortex using [3H]-LY 278584 as radioligand				J Med Chem 42: 2870-80 (1999) Article DOI: 10.1021/jm981098j BindingDB Entry DOI: 10.7270/Q24X58GN
					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50079298 (3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...) Show SMILES CC(C)n1c2ccccc2n(C(=O)NCCCN2CCN(C)CC2)c1=O Show InChI InChI=1S/C19H29N5O2/c1-15(2)23-16-7-4-5-8-17(16)24(19(23)26)18(25)20-9-6-10-22-13-11-21(3)12-14-22/h4-5,7-8,15H,6,9-14H2,1-3H3,(H,20,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FAES, S.A. Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5-hydroxytryptamine 4 receptor in guinea pig striatum				J Med Chem 42: 2870-80 (1999) Article DOI: 10.1021/jm981098j BindingDB Entry DOI: 10.7270/Q24X58GN
					More data for this Ligand-Target Pair