BindingDB logo
myBDB logout

null

SMILES: Cc1ccccc1\C(=C/OCCN1CCC=C(C1)C(O)=O)c1cccc(Cl)c1

InChI Key: InChIKey=VEZOMALKZRINDK-JWGURIENSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080341   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent GABA transporter 1


(Rattus norvegicus)		BDBM50080341
PNG
(1-{2-[(Z)-2-(3-Chloro-phenyl)-2-o-tolyl-vinyloxy]-...)
Show SMILES Cc1ccccc1\C(=C/OCCN1CCC=C(C1)C(O)=O)c1cccc(Cl)c1 |c:16|
Show InChI InChI=1S/C23H24ClNO3/c1-17-6-2-3-10-21(17)22(18-7-4-9-20(24)14-18)16-28-13-12-25-11-5-8-19(15-25)23(26)27/h2-4,6-10,14,16H,5,11-13,15H2,1H3,(H,26,27)/b22-16-
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 64n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes

J Med Chem 42: 3447-62 (1999)


Article DOI: 10.1021/jm981027k
BindingDB Entry DOI: 10.7270/Q2057GMV
More data for this
Ligand-Target Pair