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BDBM50080347 (R)-1-(5,5-Diphenyl-pent-4-enyl)-piperidine-3-carboxylic acid; hydrochloride::CHEMBL539539

SMILES: [#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]\[#6]=[#6](\c2ccccc2)-c2ccccc2)-[#6]-1

InChI Key: InChIKey=UFKPKYJUWAOPRE-OAQYLSRUSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080347   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent GABA transporter 1


(Rattus norvegicus)		BDBM50080347
PNG
((R)-1-(5,5-Diphenyl-pent-4-enyl)-piperidine-3-carb...)
Show SMILES [#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]\[#6]=[#6](\c2ccccc2)-c2ccccc2)-[#6]-1
Show InChI InChI=1S/C23H27NO2/c25-23(26)21-14-9-17-24(18-21)16-8-7-15-22(19-10-3-1-4-11-19)20-12-5-2-6-13-20/h1-6,10-13,15,21H,7-9,14,16-18H2,(H,25,26)/t21-/m1/s1
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Similars
Article
PubMed
>100n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes

J Med Chem 42: 3447-62 (1999)


Article DOI: 10.1021/jm981027k
BindingDB Entry DOI: 10.7270/Q2057GMV
More data for this
Ligand-Target Pair