BindingDB logo
myBDB logout

null

SMILES: [#6]-[#6]-c1ccccc1\[#6](=[#6]\[#8]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]=[#6](-[#6]-1)-[#6](-[#8])=O)-c1ccccc1-[#6]-[#6]

InChI Key: InChIKey=LYTBTINBQJGDLC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080359   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent GABA transporter 1


(Rattus norvegicus)		BDBM50080359
PNG
(1-{2-[2,2-Bis-(2-ethyl-phenyl)-vinyloxy]-ethyl}-1,...)
Show SMILES [#6]-[#6]-c1ccccc1\[#6](=[#6]\[#8]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]=[#6](-[#6]-1)-[#6](-[#8])=O)-c1ccccc1-[#6]-[#6] |c:17|
Show InChI InChI=1S/C26H31NO3/c1-3-20-10-5-7-13-23(20)25(24-14-8-6-11-21(24)4-2)19-30-17-16-27-15-9-12-22(18-27)26(28)29/h5-8,10-14,19H,3-4,9,15-18H2,1-2H3,(H,28,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 47n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes

J Med Chem 42: 3447-62 (1999)


Article DOI: 10.1021/jm981027k
BindingDB Entry DOI: 10.7270/Q2057GMV
More data for this
Ligand-Target Pair