BDBM50080820 CHEMBL3422476

SMILES: OC(=O)c1ccc(o1)-c1ccc(C(=S)NCc2ccc(cc2)-c2ccnn2-c2ccc(Cl)c(Cl)c2)c(Cl)c1

InChI Key: InChIKey=XXQKNGSPGDXDMG-UHFFFAOYSA-N

Data: 1 Kd

PDB links: 1 PDB ID matches this monomer.

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50080820 (CHEMBL3422476) Show SMILES OC(=O)c1ccc(o1)-c1ccc(C(=S)NCc2ccc(cc2)-c2ccnn2-c2ccc(Cl)c(Cl)c2)c(Cl)c1 Show InChI InChI=1S/C28H18Cl3N3O3S/c29-21-8-6-19(14-23(21)31)34-24(11-12-33-34)17-3-1-16(2-4-17)15-32-27(38)20-7-5-18(13-22(20)30)25-9-10-26(37-25)28(35)36/h1-14H,15H2,(H,32,38)(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N protein (unknown origin) incubated for 1 hr using FITC-ATRIP/FITC-ATRIP2 peptide probe by fluorescence polarization anisot...				ACS Med Chem Lett 6: 140-5 (2015) Article DOI: 10.1021/ml5003629 BindingDB Entry DOI: 10.7270/Q2HM5B5R
					More data for this Ligand-Target Pair				3D Structure (crystal)