BDBM50080823 CHEMBL3422474

SMILES: OC(=O)c1cc(-c2ccc(CNC(=S)c3ccc(cc3)-c3nnn[nH]3)cc2)n(n1)-c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=VYNWLYGZBSRGNF-UHFFFAOYSA-N

Data: 1 Kd

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50080823 (CHEMBL3422474) Show SMILES OC(=O)c1cc(-c2ccc(CNC(=S)c3ccc(cc3)-c3nnn[nH]3)cc2)n(n1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H17Cl2N7O2S/c26-19-10-9-18(11-20(19)27)34-22(12-21(31-34)25(35)36)15-3-1-14(2-4-15)13-28-24(37)17-7-5-16(6-8-17)23-29-32-33-30-23/h1-12H,13H2,(H,28,37)(H,35,36)(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N protein (unknown origin) incubated for 1 hr using FITC-ATRIP/FITC-ATRIP2 peptide probe by fluorescence polarization anisot...				ACS Med Chem Lett 6: 140-5 (2015) Article DOI: 10.1021/ml5003629 BindingDB Entry DOI: 10.7270/Q2HM5B5R
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