BDBM50080838 3-(4-Benzyl-piperidin-1-yl)-N-{6-[3-(4-benzyl-piperidin-1-yl)-propionylamino]-acridin-3-yl}-propionamide::CHEMBL310569::N,N'-(acridine-3,6-diyl)bis(3-(4-benzylpiperidin-1-yl)propanamide)

SMILES: O=C(CCN1CCC(Cc2ccccc2)CC1)Nc1ccc2cc3ccc(NC(=O)CCN4CCC(Cc5ccccc5)CC4)cc3nc2c1

InChI Key: InChIKey=YODPLRICWXOARC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50080838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50080838 (3-(4-Benzyl-piperidin-1-yl)-N-{6-[3-(4-benzyl-pipe...) Show SMILES O=C(CCN1CCC(Cc2ccccc2)CC1)Nc1ccc2cc3ccc(NC(=O)CCN4CCC(Cc5ccccc5)CC4)cc3nc2c1 Show InChI InChI=1S/C43H49N5O2/c49-42(19-25-47-21-15-34(16-22-47)27-32-7-3-1-4-8-32)44-38-13-11-36-29-37-12-14-39(31-41(37)46-40(36)30-38)45-43(50)20-26-48-23-17-35(18-24-48)28-33-9-5-2-6-10-33/h1-14,29-31,34-35H,15-28H2,(H,44,49)(H,45,50)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Las Villas Curated by ChEMBL					Assay Description Inhibition of telomerase in human A2780 cells by TRAP assay				Eur J Med Chem 44: 4826-40 (2009) Article DOI: 10.1016/j.ejmech.2009.07.029 BindingDB Entry DOI: 10.7270/Q20R9PHM
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50080838 (3-(4-Benzyl-piperidin-1-yl)-N-{6-[3-(4-benzyl-pipe...) Show SMILES O=C(CCN1CCC(Cc2ccccc2)CC1)Nc1ccc2cc3ccc(NC(=O)CCN4CCC(Cc5ccccc5)CC4)cc3nc2c1 Show InChI InChI=1S/C43H49N5O2/c49-42(19-25-47-21-15-34(16-22-47)27-32-7-3-1-4-8-32)44-38-13-11-36-29-37-12-14-39(31-41(37)46-40(36)30-38)45-43(50)20-26-48-23-17-35(18-24-48)28-33-9-5-2-6-10-33/h1-14,29-31,34-35H,15-28H2,(H,44,49)(H,45,50)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Ability to inhibit human telomerase in a modified cell-free TRAP assay using extracts from A2780 cell line				Bioorg Med Chem Lett 9: 2463-8 (1999) BindingDB Entry DOI: 10.7270/Q2H41QN7
					More data for this Ligand-Target Pair