BDBM50080861 CHEMBL3422462

SMILES: OC(=O)c1cc(-c2ccc(CNS(=O)(=O)c3ccccc3)cc2)n(n1)-c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=QIKFKERWBDPFPQ-UHFFFAOYSA-N

Data: 1 Kd

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50080861 (CHEMBL3422462) Show SMILES OC(=O)c1cc(-c2ccc(CNS(=O)(=O)c3ccccc3)cc2)n(n1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H17Cl2N3O4S/c24-19-11-10-17(12-20(19)25)28-22(13-21(27-28)23(29)30)16-8-6-15(7-9-16)14-26-33(31,32)18-4-2-1-3-5-18/h1-13,26H,14H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N protein (unknown origin) incubated for 1 hr using FITC-ATRIP/FITC-ATRIP2 peptide probe by fluorescence polarization anisot...				ACS Med Chem Lett 6: 140-5 (2015) Article DOI: 10.1021/ml5003629 BindingDB Entry DOI: 10.7270/Q2HM5B5R
					More data for this Ligand-Target Pair