BDBM50081402 CHEMBL3422002

SMILES: Cc1ccnc(c1)-c1nnc2CN(CCn12)C(=O)c1ccc(F)cc1

InChI Key: InChIKey=VGMVORMYEVYVFG-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50081402 (CHEMBL3422002) Show SMILES Cc1ccnc(c1)-c1nnc2CN(CCn12)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C18H16FN5O/c1-12-6-7-20-15(10-12)17-22-21-16-11-23(8-9-24(16)17)18(25)13-2-4-14(19)5-3-13/h2-7,10H,8-9,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Euroscreen SA Curated by ChEMBL					Assay Description Displacement of [3H]-SB222200 from recombinant human NK3R expressed in CHO cell membranes after 90 mins by scintillation counting analysis				J Med Chem 58: 3060-82 (2015) Article DOI: 10.1021/jm5017413 BindingDB Entry DOI: 10.7270/Q2ZP47TC
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50081402 (CHEMBL3422002) Show SMILES Cc1ccnc(c1)-c1nnc2CN(CCn12)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C18H16FN5O/c1-12-6-7-20-15(10-12)17-22-21-16-11-23(8-9-24(16)17)18(25)13-2-4-14(19)5-3-13/h2-7,10H,8-9,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Euroscreen SA Curated by ChEMBL					Assay Description Antagonist activity at recombinant human NK3R expressed in CHO cells assessed as inhibition of NKB-induced Ca2+ signaling by aequorin Ca2+ biolumines...				J Med Chem 58: 3060-82 (2015) Article DOI: 10.1021/jm5017413 BindingDB Entry DOI: 10.7270/Q2ZP47TC
					More data for this Ligand-Target Pair