null

SMILES: Fc1ccc2c(c1)nc(N1CCN(Cc3ccco3)CC1)c1cccn21

InChI Key: InChIKey=JVWDIVYJDNVJIC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A/3B (Homo sapiens (Human))	BDBM50081971 (7-Fluoro-4-(4-furan-2-ylmethyl-piperazin-1-yl)-pyr...) Show SMILES Fc1ccc2c(c1)nc(N1CCN(Cc3ccco3)CC1)c1cccn21 Show InChI InChI=1S/C20H19FN4O/c21-15-5-6-18-17(13-15)22-20(19-4-1-7-25(18)19)24-10-8-23(9-11-24)14-16-3-2-12-26-16/h1-7,12-13H,8-11,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.60	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]-guanidinium uptake on NG108-15 cells.				J Med Chem 42: 4362-79 (1999) BindingDB Entry DOI: 10.7270/Q2S75FJM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50081971 (7-Fluoro-4-(4-furan-2-ylmethyl-piperazin-1-yl)-pyr...) Show SMILES Fc1ccc2c(c1)nc(N1CCN(Cc3ccco3)CC1)c1cccn21 Show InChI InChI=1S/C20H19FN4O/c21-15-5-6-18-17(13-15)22-20(19-4-1-7-25(18)19)24-10-8-23(9-11-24)14-16-3-2-12-26-16/h1-7,12-13H,8-11,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligand				J Med Chem 42: 4362-79 (1999) BindingDB Entry DOI: 10.7270/Q2S75FJM
					More data for this Ligand-Target Pair