BDBM50081983 4-(4-Methyl-piperazin-1-yl)-imidazo[1,2-a]quinoxaline::CHEMBL136525

SMILES: CN1CCN(CC1)c1nc2ccccc2n2ccnc12

InChI Key: InChIKey=LEYLGASDPIBOMV-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50081983 (4-(4-Methyl-piperazin-1-yl)-imidazo[1,2-a]quinoxal...) Show SMILES CN1CCN(CC1)c1nc2ccccc2n2ccnc12 Show InChI InChI=1S/C15H17N5/c1-18-8-10-19(11-9-18)15-14-16-6-7-20(14)13-5-3-2-4-12(13)17-15/h2-7H,8-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligand				J Med Chem 42: 4362-79 (1999) BindingDB Entry DOI: 10.7270/Q2S75FJM
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Homo sapiens (Human))	BDBM50081983 (4-(4-Methyl-piperazin-1-yl)-imidazo[1,2-a]quinoxal...) Show SMILES CN1CCN(CC1)c1nc2ccccc2n2ccnc12 Show InChI InChI=1S/C15H17N5/c1-18-8-10-19(11-9-18)15-14-16-6-7-20(14)13-5-3-2-4-12(13)17-15/h2-7H,8-11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]-guanidinium uptake on NG108-15 cells.				J Med Chem 42: 4362-79 (1999) BindingDB Entry DOI: 10.7270/Q2S75FJM
					More data for this Ligand-Target Pair