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SMILES: Oc1c(-c2cccc(Oc3cccc(NC(=O)CCl)c3)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key: InChIKey=WKNUHBCPLHAZPT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082027   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50082027
PNG
(2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Show SMILES Oc1c(-c2cccc(Oc3cccc(NC(=O)CCl)c3)c2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-15-4-2-6-17(11-15)31-16-5-1-3-13(9-16)21-22(29)18-8-7-14(25)10-19(18)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 13.8n/an/an/an/an/an/an/an/a



Université Louis Pasteur

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...

J Med Chem 42: 4394-404 (1999)


BindingDB Entry DOI: 10.7270/Q2HT2NJB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50082027
PNG
(2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Show SMILES Oc1c(-c2cccc(Oc3cccc(NC(=O)CCl)c3)c2)c(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-15-4-2-6-17(11-15)31-16-5-1-3-13(9-16)21-22(29)18-8-7-14(25)10-19(18)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 39n/an/an/an/an/an/a



Université Louis Pasteur

Curated by ChEMBL


Assay Description
Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...

J Med Chem 42: 4394-404 (1999)


BindingDB Entry DOI: 10.7270/Q2HT2NJB
More data for this
Ligand-Target Pair