BDBM50082111 CHEMBL3422630
SMILES: COCC(=O)N1CCN(CC1)C(=O)[C@H]1CC[C@H](Cn2c(=O)n(C)c3ccc(OC)cc3c2=O)CC1
InChI Key: InChIKey=CYIHQUXKBWFESS-IYARVYRRSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human)) | BDBM50082111![]() (CHEMBL3422630) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sienabiotech S.p.A. Curated by ChEMBL | Assay Description Inhibition of GST-tagged Tankyrases 2 (unknown origin) by autoPARsylationassay | Eur J Med Chem 95: 526-45 (2015) Article DOI: 10.1016/j.ejmech.2015.03.055 BindingDB Entry DOI: 10.7270/Q28W3G1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human)) | BDBM50082111![]() (CHEMBL3422630) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sienabiotech S.p.A. Curated by ChEMBL | Assay Description Inhibition of GST-tagged Tankyrases 1 (unknown origin) by autoPARsylationassay | Eur J Med Chem 95: 526-45 (2015) Article DOI: 10.1016/j.ejmech.2015.03.055 BindingDB Entry DOI: 10.7270/Q28W3G1F | |||||||||||
More data for this Ligand-Target Pair |