BDBM50083279 Adamantane-1-carboxylic acid {2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl}-amide; Dihydrochloride::CHEMBL545327

SMILES: O=C(NCCCN1CCN(CC1)c1ncccn1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI Key: InChIKey=GXNAWFJEYSRWFN-VTIBSLLJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50083279 (Adamantane-1-carboxylic acid {2-[4-(3-chloro-pheny...) Show SMILES O=C(NCCCN1CCN(CC1)c1ncccn1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |TLB:21:22:26:19.20.25,THB:21:20:26:27.22.23| Show InChI InChI=1S/C22H33N5O/c28-20(22-14-17-11-18(15-22)13-19(12-17)16-22)23-5-2-6-26-7-9-27(10-8-26)21-24-3-1-4-25-21/h1,3-4,17-19H,2,5-16H2,(H,23,28)/t17-,18+,19-,22?	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
					More data for this Ligand-Target Pair