BDBM50083282 CHEMBL558411::Hexahydro-2,5-methano-pentalene-3a-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide; dihydrochloride
SMILES: COc1ccccc1N1CCN(CCCNC(=O)C23CC4C[C@@H]2C[C@@H](C3)C4)CC1
InChI Key: InChIKey=ZJOCEDFOQUAJHZ-FKOHWTJXSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50083282 (CHEMBL558411 | Hexahydro-2,5-methano-pentalene-3a-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor | J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P | |||||||||||
More data for this Ligand-Target Pair |