BDBM50083291 Adamantane-1-carboxylic acid [(R)-1-methyl-2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-amide::CHEMBL356575

SMILES: C[C@H](CN1CCN(CC1)c1ncccn1)NC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI Key: InChIKey=VZUHPBSTYDQEJX-XDIMERGTSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50083291 (Adamantane-1-carboxylic acid [(R)-1-methyl-2-(4-py...) Show SMILES C[C@H](CN1CCN(CC1)c1ncccn1)NC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |TLB:25:24:27:19.20.21,25:20:27:26.24.23| Show InChI InChI=1S/C22H33N5O/c1-16(15-26-5-7-27(8-6-26)21-23-3-2-4-24-21)25-20(28)22-12-17-9-18(13-22)11-19(10-17)14-22/h2-4,16-19H,5-15H2,1H3,(H,25,28)/t16-,17-,18+,19-,22?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50083291 (Adamantane-1-carboxylic acid [(R)-1-methyl-2-(4-py...) Show SMILES C[C@H](CN1CCN(CC1)c1ncccn1)NC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |TLB:25:24:27:19.20.21,25:20:27:26.24.23| Show InChI InChI=1S/C22H33N5O/c1-16(15-26-5-7-27(8-6-26)21-23-3-2-4-24-21)25-20(28)22-12-17-9-18(13-22)11-19(10-17)14-22/h2-4,16-19H,5-15H2,1H3,(H,25,28)/t16-,17-,18+,19-,22?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	153	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against rat limbic tissue Dopamine receptor D2				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
					More data for this Ligand-Target Pair