BDBM50083306 CHEMBL553024::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2-(3-methyl-adamantan-1-yl)-acetamide; Dihydrochloride

SMILES: COc1ccccc1N1CCN(CCNC(=O)CC23C[C@H]4C[C@H](C[C@](C)(C4)C2)C3)CC1

InChI Key: InChIKey=GMQIRCYDFOUIEG-ZBDAUQGMSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50083306 (CHEMBL553024 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)CC23C[C@H]4C[C@H](C[C@](C)(C4)C2)C3)CC1 |TLB:25:24:19:22.28.21,THB:23:24:19:22.28.21,23:22:19:24.27.26| Show InChI InChI=1S/C26H39N3O2/c1-25-14-20-13-21(15-25)17-26(16-20,19-25)18-24(30)27-7-8-28-9-11-29(12-10-28)22-5-3-4-6-23(22)31-2/h3-6,20-21H,7-19H2,1-2H3,(H,27,30)/t20-,21+,25-,26?	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
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