BDBM50083336 6-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one::CHEMBL348435

SMILES: COc1ccc(cc1)N1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1

InChI Key: InChIKey=MOWGNBXIJRPPMR-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083336 (6-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-b...) Show SMILES COc1ccc(cc1)N1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C20H23N3O3/c1-25-17-5-3-16(4-6-17)23-10-8-22(9-11-23)13-15-2-7-19-18(12-15)21-20(24)14-26-19/h2-7,12H,8-11,13-14H2,1H3,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50083336 (6-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-b...) Show SMILES COc1ccc(cc1)N1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C20H23N3O3/c1-25-17-5-3-16(4-6-17)23-10-8-22(9-11-23)13-15-2-7-19-18(12-15)21-20(24)14-26-19/h2-7,12H,8-11,13-14H2,1H3,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>3.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D3 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50083336 (6-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-b...) Show SMILES COc1ccc(cc1)N1CCN(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C20H23N3O3/c1-25-17-5-3-16(4-6-17)23-10-8-22(9-11-23)13-15-2-7-19-18(12-15)21-20(24)14-26-19/h2-7,12H,8-11,13-14H2,1H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D2 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair