BindingDB PrimarySearch

BDBM50083518 4'-Chloro-4-((E)-4-phenyl-but-1-enyl)-biphenyl-2-carboxylic acid ethylamide::4'-Chloro-4-(4-phenyl-but-1-enyl)-biphenyl-2-carboxylic acid ethylamide::CHEMBL418444

SMILES: CCNC(=O)c1cc(\C=C\CCc2ccccc2)ccc1-c1ccc(Cl)cc1

InChI Key: InChIKey=MUHGPSGAIHTOED-YRNVUSSQSA-N

Data: 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083518
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50083518 (4'-Chloro-4-((E)-4-phenyl-but-1-enyl)-biphenyl-2-c...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro immunosuppression in stimulated T cells expressing Voltage-gated potassium channel subunit Kv1.3; Range is 1-10				J Med Chem 44: 1627-53 (2001) BindingDB Entry DOI: 10.7270/Q218376D
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50083518 (4'-Chloro-4-((E)-4-phenyl-but-1-enyl)-biphenyl-2-c...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of [125I]- ChTX from human T cell voltage-gated potassium channel subunit Kv1.3				Bioorg Med Chem Lett 9: 3267-72 (2000) BindingDB Entry DOI: 10.7270/Q2765DJW
University of California Curated by ChEMBL					More data for this Ligand-Target Pair