BDBM50083578 4-{5-[(4-Benzenesulfonyl-phenylamino)-methyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL112940

SMILES: O=S(=O)(c1ccccc1)c1ccc(NCc2cncn2Cc2ccc(cc2)C#N)cc1

InChI Key: InChIKey=ZDHCZPBJZQRBMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50083578 (4-{5-[(4-Benzenesulfonyl-phenylamino)-methyl]-imid...) Show SMILES O=S(=O)(c1ccccc1)c1ccc(NCc2cncn2Cc2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C24H20N4O2S/c25-14-19-6-8-20(9-7-19)17-28-18-26-15-22(28)16-27-21-10-12-24(13-11-21)31(29,30)23-4-2-1-3-5-23/h1-13,15,18,27H,16-17H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Farnesyltransferase in vitro.				Bioorg Med Chem Lett 9: 3301-6 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NT7
					More data for this Ligand-Target Pair