BDBM50083980 CHEMBL535353::N-(5-Amino-pentyl)-2-(6-bromo-2-naphthalen-2-yl-4-oxo-4H-quinazolin-3-yl)-acetamide; hydrochloride

SMILES: NCCCCCNC(=O)Cn1c(nc2ccc(Br)cc2c1=O)-c1ccc2ccccc2c1

InChI Key: InChIKey=MRFLXHSGRLWBQR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50083980 (CHEMBL535353 | N-(5-Amino-pentyl)-2-(6-bromo-2-nap...) Show SMILES NCCCCCNC(=O)Cn1c(nc2ccc(Br)cc2c1=O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C25H25BrN4O2/c26-20-10-11-22-21(15-20)25(32)30(16-23(31)28-13-5-1-4-12-27)24(29-22)19-9-8-17-6-2-3-7-18(17)14-19/h2-3,6-11,14-15H,1,4-5,12-13,16,27H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor				Bioorg Med Chem Lett 10: 5-8 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KDR
					More data for this Ligand-Target Pair