null

SMILES: COc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC(C)(C)C

InChI Key: InChIKey=WXUQPWYPRTYWIR-JVVDOCDTSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50084201 ((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC(C)(C)C Show InChI InChI=1S/C16H23N3O6S/c1-16(2,3)25-18-11-9-14(15(20)17-21)19(10-11)26(22,23)13-7-5-12(24-4)6-8-13/h5-8,14,21H,9-10H2,1-4H3,(H,17,20)/b18-11-/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition activity of human recombinant stromelysin (Matrix metalloproteinase-3)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50084201 ((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC(C)(C)C Show InChI InChI=1S/C16H23N3O6S/c1-16(2,3)25-18-11-9-14(15(20)17-21)19(10-11)26(22,23)13-7-5-12(24-4)6-8-13/h5-8,14,21H,9-10H2,1-4H3,(H,17,20)/b18-11-/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition of matrilysin (Matrix metalloproteinase-7, MMP-7)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50084201 ((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC(C)(C)C Show InChI InChI=1S/C16H23N3O6S/c1-16(2,3)25-18-11-9-14(15(20)17-21)19(10-11)26(22,23)13-7-5-12(24-4)6-8-13/h5-8,14,21H,9-10H2,1-4H3,(H,17,20)/b18-11-/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084201 ((R)-4-[(Z)-tert-Butoxyimino]-1-(4-methoxy-benzenes...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC(C)(C)C Show InChI InChI=1S/C16H23N3O6S/c1-16(2,3)25-18-11-9-14(15(20)17-21)19(10-11)26(22,23)13-7-5-12(24-4)6-8-13/h5-8,14,21H,9-10H2,1-4H3,(H,17,20)/b18-11-/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibitory activity against gelatinase-A (matrix metalloproteinase-2).				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair