null

SMILES: CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO

InChI Key: InChIKey=YBRVBUDXSMPLGQ-YPFLROGLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50084207 ((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(4-fluoro-phenox...) Show SMILES CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO Show InChI InChI=1S/C21H24FN3O6S/c1-21(2,3)31-24-15-12-19(20(26)23-27)25(13-15)32(28,29)18-10-8-17(9-11-18)30-16-6-4-14(22)5-7-16/h4-11,19,27H,12-13H2,1-3H3,(H,23,26)/b24-15-/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant collagenase-3 (Matrix metalloproteinase-13)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50084207 ((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(4-fluoro-phenox...) Show SMILES CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO Show InChI InChI=1S/C21H24FN3O6S/c1-21(2,3)31-24-15-12-19(20(26)23-27)25(13-15)32(28,29)18-10-8-17(9-11-18)30-16-6-4-14(22)5-7-16/h4-11,19,27H,12-13H2,1-3H3,(H,23,26)/b24-15-/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50084207 ((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(4-fluoro-phenox...) Show SMILES CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO Show InChI InChI=1S/C21H24FN3O6S/c1-21(2,3)31-24-15-12-19(20(26)23-27)25(13-15)32(28,29)18-10-8-17(9-11-18)30-16-6-4-14(22)5-7-16/h4-11,19,27H,12-13H2,1-3H3,(H,23,26)/b24-15-/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition of matrilysin (Matrix metalloproteinase-7, MMP-7)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair