null

SMILES: CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccncc2)cc1)C(=O)NO

InChI Key: InChIKey=BUOKQWSUTKFXOW-NLKUQUHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrilysin (Homo sapiens (Human))	BDBM50084215 ((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(pyridin-4-yloxy...) Show SMILES CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccncc2)cc1)C(=O)NO Show InChI InChI=1S/C20H24N4O6S/c1-20(2,3)30-23-14-12-18(19(25)22-26)24(13-14)31(27,28)17-6-4-15(5-7-17)29-16-8-10-21-11-9-16/h4-11,18,26H,12-13H2,1-3H3,(H,22,25)/b23-14-/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	785	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition of matrilysin (Matrix metalloproteinase-7, MMP-7)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084215 ((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(pyridin-4-yloxy...) Show SMILES CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccncc2)cc1)C(=O)NO Show InChI InChI=1S/C20H24N4O6S/c1-20(2,3)30-23-14-12-18(19(25)22-26)24(13-14)31(27,28)17-6-4-15(5-7-17)29-16-8-10-21-11-9-16/h4-11,18,26H,12-13H2,1-3H3,(H,22,25)/b23-14-/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition activity of human recombinant stromelysin (Matrix metalloproteinase-3)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50084215 ((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(pyridin-4-yloxy...) Show SMILES CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccncc2)cc1)C(=O)NO Show InChI InChI=1S/C20H24N4O6S/c1-20(2,3)30-23-14-12-18(19(25)22-26)24(13-14)31(27,28)17-6-4-15(5-7-17)29-16-8-10-21-11-9-16/h4-11,18,26H,12-13H2,1-3H3,(H,22,25)/b23-14-/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)				J Med Chem 42: 5426-36 (2000) BindingDB Entry DOI: 10.7270/Q2Q23ZGT
					More data for this Ligand-Target Pair