BDBM50085179 CHEMBL159537::{Cyclohexyl-[2-methoxy-4-(quinolin-2-ylmethoxy)-phenyl]-methoxyimino}-acetic acid

SMILES: COc1cc(OCc2ccc3ccccc3n2)ccc1C(O\N=C\C(O)=O)C1CCCCC1

InChI Key: InChIKey=OMFMRSCTQHDFIR-JVWAILMASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50085179 (CHEMBL159537 | {Cyclohexyl-[2-methoxy-4-(quinolin-...) Show SMILES COc1cc(OCc2ccc3ccccc3n2)ccc1C(O\N=C\C(O)=O)C1CCCCC1 Show InChI InChI=1S/C26H28N2O5/c1-31-24-15-21(32-17-20-12-11-18-7-5-6-10-23(18)28-20)13-14-22(24)26(33-27-16-25(29)30)19-8-3-2-4-9-19/h5-7,10-16,19,26H,2-4,8-9,17H2,1H3,(H,29,30)/b27-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair