BDBM50085182 (E)-4-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-methoxyimino}-pentanoic acid::(Z)-4-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-methoxyimino}-pentanoic acid::CHEMBL159376

SMILES: C\C(CCC(O)=O)=N/OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1

InChI Key: InChIKey=UUODXXOKNMRECJ-TWKHWXDSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50085182 ((E)-4-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES C\C(CCC(O)=O)=N/OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C28H32N2O4/c1-20(11-18-27(31)32)30-34-28(22-8-3-2-4-9-22)23-13-16-25(17-14-23)33-19-24-15-12-21-7-5-6-10-26(21)29-24/h5-7,10,12-17,22,28H,2-4,8-9,11,18-19H2,1H3,(H,31,32)/b30-20+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair