BDBM50085188 CHEMBL163758::{Cyclohexyl-[4-(quinoxalin-2-ylmethoxy)-phenyl]-methoxyimino}-acetic acid

SMILES: OC(=O)\C=N\OC(C1CCCCC1)c1ccc(OCc2cnc3ccccc3n2)cc1

InChI Key: InChIKey=YNCOFMIKOWLKMV-CVKSISIWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50085188 (CHEMBL163758 | {Cyclohexyl-[4-(quinoxalin-2-ylmeth...) Show SMILES OC(=O)\C=N\OC(C1CCCCC1)c1ccc(OCc2cnc3ccccc3n2)cc1 Show InChI InChI=1S/C24H25N3O4/c28-23(29)15-26-31-24(17-6-2-1-3-7-17)18-10-12-20(13-11-18)30-16-19-14-25-21-8-4-5-9-22(21)27-19/h4-5,8-15,17,24H,1-3,6-7,16H2,(H,28,29)/b26-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair