BindingDB logo
myBDB logout

BDBM50085209 CHEMBL422536::{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-methoxyimino}-phenyl-acetic acid (0.5H2O)

SMILES: OC(=O)C(=N\OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1)\c1ccccc1

InChI Key: InChIKey=AEVHAKXZQAPBIQ-XPXRSFDGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085209   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))		BDBM50085209
PNG
(CHEMBL422536 | {Cyclohexyl-[4-(quinolin-2-ylmethox...)
Show SMILES OC(=O)C(=N\OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1)\c1ccccc1
Show InChI InChI=1S/C31H30N2O4/c34-31(35)29(23-10-3-1-4-11-23)33-37-30(24-12-5-2-6-13-24)25-16-19-27(20-17-25)36-21-26-18-15-22-9-7-8-14-28(22)32-26/h1,3-4,7-11,14-20,24,30H,2,5-6,12-13,21H2,(H,34,35)/b33-29+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 31n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay

J Med Chem 43: 690-705 (2000)


BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair