BDBM50085212 2-{[4-(Quinolin-2-ylmethoxy)-phenyl]-thiophen-2-yl-methoxyimino}-propionic acid::CHEMBL159535

SMILES: C\C(=N/OC(c1cccs1)c1ccc(OCc2ccc3ccccc3n2)cc1)C(O)=O

InChI Key: InChIKey=SLKBLIXGHFOAKA-WGOQTCKBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50085212 (2-{[4-(Quinolin-2-ylmethoxy)-phenyl]-thiophen-2-yl...) Show SMILES C\C(=N/OC(c1cccs1)c1ccc(OCc2ccc3ccccc3n2)cc1)C(O)=O Show InChI InChI=1S/C24H20N2O4S/c1-16(24(27)28)26-30-23(22-7-4-14-31-22)18-9-12-20(13-10-18)29-15-19-11-8-17-5-2-3-6-21(17)25-19/h2-14,23H,15H2,1H3,(H,27,28)/b26-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair