BDBM50085226 CHEMBL348398::{[2-Chloro-4-(5-fluoro-benzothiazol-2-ylmethoxy)-phenyl]-cyclohexyl-methoxyimino}-acetic acid

SMILES: OC(=O)\C=N\OC(C1CCCCC1)c1ccc(OCc2nc3cc(F)ccc3s2)cc1Cl

InChI Key: InChIKey=XOKJFANORKEQFM-RPPGKUMJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50085226 (CHEMBL348398 | {[2-Chloro-4-(5-fluoro-benzothiazol...) Show SMILES OC(=O)\C=N\OC(C1CCCCC1)c1ccc(OCc2nc3cc(F)ccc3s2)cc1Cl Show InChI InChI=1S/C23H22ClFN2O4S/c24-18-11-16(30-13-21-27-19-10-15(25)6-9-20(19)32-21)7-8-17(18)23(31-26-12-22(28)29)14-4-2-1-3-5-14/h6-12,14,23H,1-5,13H2,(H,28,29)/b26-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair