BDBM50085228 (Cyclohexyl-{4-[4-(4-isopropyl-phenyl)-thiazol-2-ylmethoxy]-phenyl}-methoxyimino)-acetic acid (2H2O)::CHEMBL423605

SMILES: CC(C)c1ccc(cc1)-c1csc(COc2ccc(cc2)C(O\N=C\C(O)=O)C2CCCCC2)n1

InChI Key: InChIKey=UTFRKCHZGFOPGF-MUFRIFMGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50085228 ((Cyclohexyl-{4-[4-(4-isopropyl-phenyl)-thiazol-2-y...) Show SMILES CC(C)c1ccc(cc1)-c1csc(COc2ccc(cc2)C(O\N=C\C(O)=O)C2CCCCC2)n1 Show InChI InChI=1S/C28H32N2O4S/c1-19(2)20-8-10-21(11-9-20)25-18-35-26(30-25)17-33-24-14-12-23(13-15-24)28(34-29-16-27(31)32)22-6-4-3-5-7-22/h8-16,18-19,22,28H,3-7,17H2,1-2H3,(H,31,32)/b29-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair