BDBM50085230 2-{2-Butyl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-hexyloxyimino}-propionic acid (2H2O)::CHEMBL355374

SMILES: CCCCC(CCCC)C(O\N=C(/C)C(O)=O)c1ccc(OCc2ccc3ccccc3n2)cc1

InChI Key: InChIKey=HIYFSMZDGZFVDT-NJZRLIGZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50085230 (2-{2-Butyl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCC(CCCC)C(O\N=C(/C)C(O)=O)c1ccc(OCc2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C29H36N2O4/c1-4-6-10-23(11-7-5-2)28(35-31-21(3)29(32)33)24-15-18-26(19-16-24)34-20-25-17-14-22-12-8-9-13-27(22)30-25/h8-9,12-19,23,28H,4-7,10-11,20H2,1-3H3,(H,32,33)/b31-21+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair