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BDBM50085232 7-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-methoxyimino}-octanoic acid (0.25H2O)::CHEMBL163164

SMILES: C\C(CCCCCC(O)=O)=N/OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1

InChI Key: InChIKey=YJNOARVPAWCNBM-GZZLJNBRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085232   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))		BDBM50085232
PNG
(7-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-me...)
Show SMILES C\C(CCCCCC(O)=O)=N/OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1
Show InChI InChI=1S/C31H38N2O4/c1-23(10-4-2-7-15-30(34)35)33-37-31(25-12-5-3-6-13-25)26-17-20-28(21-18-26)36-22-27-19-16-24-11-8-9-14-29(24)32-27/h8-9,11,14,16-21,25,31H,2-7,10,12-13,15,22H2,1H3,(H,34,35)/b33-23+
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PubMed
n/an/a 17n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay

J Med Chem 43: 690-705 (2000)


BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair