BDBM50086044 CHEMBL3425678

SMILES: CN(C)CCNc1nc(\C=C\c2ccc(cc2)C(C)(C)C)nc2ccc(C)cc12

InChI Key: InChIKey=OSKZCCAKFBWWDM-GXDHUFHOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein ftsZ (Bacillus subtilis)	BDBM50086044 (CHEMBL3425678) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(cc2)C(C)(C)C)nc2ccc(C)cc12 Show InChI InChI=1S/C25H32N4/c1-18-7-13-22-21(17-18)24(26-15-16-29(5)6)28-23(27-22)14-10-19-8-11-20(12-9-19)25(2,3)4/h7-14,17H,15-16H2,1-6H3,(H,26,27,28)/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair