BDBM50086119 CHEMBL3425698

SMILES: COCCCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12

InChI Key: InChIKey=DURBPTOEENKJRD-FMIVXFBMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086119 (CHEMBL3425698) Show SMILES COCCCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12 Show InChI InChI=1S/C24H22ClN3O/c1-29-14-4-13-26-24-21-15-18-5-2-3-6-19(18)16-22(21)27-23(28-24)12-9-17-7-10-20(25)11-8-17/h2-3,5-12,15-16H,4,13-14H2,1H3,(H,26,27,28)/b12-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair