BDBM50086191 CHEMBL3425690

SMILES: CN(C)CCNc1nc(nc2ccc(C)cc12)C(=O)NCc1ccc(Cl)cc1

InChI Key: InChIKey=ZKXGEAHSWAWINX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086191 (CHEMBL3425690) Show SMILES CN(C)CCNc1nc(nc2ccc(C)cc12)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C21H24ClN5O/c1-14-4-9-18-17(12-14)19(23-10-11-27(2)3)26-20(25-18)21(28)24-13-15-5-7-16(22)8-6-15/h4-9,12H,10-11,13H2,1-3H3,(H,24,28)(H,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair