BDBM50086196 CHEMBL3425689

SMILES: [O-]C(=O)C(F)(F)F.Cc1ccc2nc(nc(NCC[NH3+])c2c1)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=RFGAWMMMPVUJQR-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086196 (CHEMBL3425689) Show SMILES [O-]C(=O)C(F)(F)F.Cc1ccc2nc(nc(NCC[NH3+])c2c1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C18H18ClN5O/c1-11-2-7-15-14(10-11)16(21-9-8-20)24-17(23-15)18(25)22-13-5-3-12(19)4-6-13/h2-7,10H,8-9,20H2,1H3,(H,22,25)(H,21,23,24)/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair