BDBM50086198 CHEMBL3425614

SMILES: CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)-c1cccs1

InChI Key: InChIKey=HZTZMSKFVZOBTO-KPKJPENVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086198 (CHEMBL3425614) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)-c1cccs1 Show InChI InChI=1S/C24H23ClN4S/c1-29(2)14-13-26-24-20-16-18(22-4-3-15-30-22)8-11-21(20)27-23(28-24)12-7-17-5-9-19(25)10-6-17/h3-12,15-16H,13-14H2,1-2H3,(H,26,27,28)/b12-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair