BDBM50086199 CHEMBL3425613

SMILES: CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)-c1ccc2ccccc2c1

InChI Key: InChIKey=GLMHSVKTJLJZLI-CXUHLZMHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086199 (CHEMBL3425613) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)-c1ccc2ccccc2c1 Show InChI InChI=1S/C30H27ClN4/c1-35(2)18-17-32-30-27-20-25(24-11-10-22-5-3-4-6-23(22)19-24)12-15-28(27)33-29(34-30)16-9-21-7-13-26(31)14-8-21/h3-16,19-20H,17-18H2,1-2H3,(H,32,33,34)/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair