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BDBM50086205 CHEMBL3425607

SMILES: CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc(ccc12)C(F)(F)F

InChI Key: InChIKey=WBONPCSUXNNEGV-BJMVGYQFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086205   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cell division protein FtsZ


(Escherichia coli)		BDBM50086205
PNG
(CHEMBL3425607)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc(ccc12)C(F)(F)F
Show InChI InChI=1S/C21H20ClF3N4/c1-29(2)12-11-26-20-17-9-6-15(21(23,24)25)13-18(17)27-19(28-20)10-5-14-3-7-16(22)8-4-14/h3-10,13H,11-12H2,1-2H3,(H,26,27,28)/b10-5+
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.28E+5n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay

ACS Med Chem Lett 6: 308-12 (2015)


Article DOI: 10.1021/ml500497s
BindingDB Entry DOI: 10.7270/Q2PV6N4C
More data for this
Ligand-Target Pair